2024年 | 2023年 | 2022年 | 2021年 |
2020年 | 2019年 | 2018年 | 2017年 | 2016年 | 2015年 | 2014年 | 2013年 | 2012年 | 2011年
2010年 | 2009年 | 2008年 | 2007年 | 2006年 | 2005年 | 2004年 | 2003年 | 2002年 | 2001年
2000年 | 1999年 | 1998年 | 1997年 | 1996年

2024年

• γ-Secretase cleaves bifunctional fatty acid-conjugated small molecules with amide bonds in mammalian cells
  Kai Tahara, Akinobu Nakamura, Xiaotong Wang, Keishi Mitamura, Yuki Ichihashi, Keiko Kano, Emi Mishiro-Sato, Kazuhiro Aoki, Yasuteru Urano, Toru Komatsu, Shinya Tsukiji*
  ACS Chemical Biology, ASAP Article link
• Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells
  Eriko Deguchi, Shuhao Lin, Daiki Hirayama, Kimiya Matsuda, Akira Tanave, Kenta Sumiyama, Shinya Tsukiji, Tetsuhisa Otani, Mikio Furuse, Alexander Sorkin, Michiyuki Matsuda, Kenta Terai*
  Cell Reports, 43, 114986 (2024) link
  bioRxiv, DOI: https://doi.org/10.1101/2024.09.25.614853 link
• Acid-activatable photosensitizers for photodynamic therapy using self-aggregates of chlorophyll‒peptide conjugates
  Miyu Nagatani, Masaru Yoshikawa, Shinya Tsukiji, Masahiro Higuchi, Hitoshi Tamiaki, Shogo Matsubara*
  Polymer Journal, Published Online link
• 細胞内シグナル分子の活性化を簡便・特異的・可逆的に誘導するSLIPT-PM法
  築地 真也
  実験医学, 42(11), 1750–1756 (2024) link
• ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate dynamics in living cells
  Moeka Ajiki, Masaru Yoshikawa, Tomoki Miyazaki, Asami Kawasaki, Kazuhiro Aoki, Fubito Nakatsu*, Shinya Tsukiji*
  RSC Chemical Biology, 5, 544–555 (2024) link
  bioRxiv, DOI: https://doi.org/10.1101/2023.12.14.571782 link

2023年

• 細胞内シグナル分子を特異的に活性化する新ツール "SLIPT"
  築地 真也
  生体の科学, 74(6), 595–601 (2023) link
• Chemogenetic manipulation of endogenous proteins in fission yeast using a self-localizing ligand-induced protein translocation system
  Akinobu Nakamura, Yuhei Goto, Hironori Sugiyama, Shinya Tsukiji, Kazuhiro Aoki*
  ACS Chemical Biology, 18, 2506–2515 (2023) link
  bioRxiv, DOI: https://doi.org/10.1101/2023.07.27.550911 link
• Hierarchical supramolecular structure comprising reduction-responsive DNA microspheres and semi-artificial glycopeptide-based micro-asters
  Ayaka Isogami, Sayuri L. Higashi, Bioru Okumura, Aya Shibata, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Shinya Tsukiji, Kazunori Matsuura, Masato Ikeda*
  Polymer Journal, 55, 1103–1107 (2023) link
• 光-化学遺伝学による細胞内タンパク質の局在操作
  吉井 達之, 築地 真也
  Chemical Biology, 16(1), 7–9 (2023)（日本ケミカルバイオロジー学会機関誌）
• Revisit of the plasmon-mediated chemical transformation of para-aminothiophenol
  Toshiki Kondo, Motoharu Inagaki, Shohei Tanaka, Shinya Tsukiji, Kenta Motobayashi, Katsuyoshi Ikeda*
  Physical Chemistry Chemical Physics, 25, 14618–14626 (2023) link
• Palmitoylation-dependent small-molecule fluorescent probes for live-cell Golgi imaging
  Shunsuke Sawada, Masaru Yoshikawa, Keita Tsutsui, Tomoki Miyazaki, Keiko Kano, Emi Mishiro-Sato, Shinya Tsukiji*
  ACS Chemical Biology, 18, 1047–1053 (2023) link
• ケモジェネティクスによる細胞夾雑環境でのタンパク質活性操作
  築地 真也
  CSJカレントレビュー「生体分子環境の化学ー分子夾雑と1分子で解き明かす生体の挙動ー」, Part II 9章, 86–92 (2023)［日本化学会 編, 化学同人］link
• Editorial overview: Synthetic biomolecules for probing lipid membranes
  Neal K. Devaraj*, Shinya Tsukiji*
  Current Opinion in Chemical Biology, 73, 102271 (2023) link
• Chemo- and opto-genetic tools for dissecting the role of membrane contact sites in living cells: recent advances and limitations
  Fubito Nakatsu*, Shinya Tsukiji
  Current Opinion in Chemical Biology, 73, 102262 (2023) link
• Miniaturized synthetic palmitoylation motifs for small-molecule localization in living cells
  Sachio Suzuki, Masaru Yoshikawa, Shunsuke Sawada, Neal K. Devaraj, Shinya Tsukiji*
  Bioconjugate Chemistry, 34, 169–173 (2023) link

2022年

• SLIPT-PMシステムを用いた細胞内シグナル操作
  築地 真也, 鈴木 祥央
  化学と工業, 75(12), 879 (2022) link
• A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
  Naoya Hino*, Kimiya Matsuda, Yuya Jikko, Gembu Maryu, Katsuya Sakai, Ryu Imamura, Shinya Tsukiji, Kazuhiro Aoki, Kenta Terai, Tsuyoshi Harashima, Xavier Trepat, Michiyuki Matsuda*
  Developmental Cell, 57, 2290–2304 (2022) link
• タンパク質活性を隔離・放出する人工相分離ドロップレット
  築地 真也, 吉川 優
  MEDCHEM NEWS, 32(3), 140–144 (2022) link
• A peptide nanocage constructed by self-assembly of oligoproline conjugates
  Shogo Matsubara*, Yui Okamoto, Masaru Yoshikawa, Shinya Tsukiji, Masahiro Higuchi
  Bioconjugate Chemistry, 33, 1785–1788 (2022) link
  
  • Selected as the Supplementary Cover link
• A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation
  Sachio Suzuki^†, Akinobu Nakamura^†, Yuka Hatano, Masaru Yoshikawa, Tatsuyuki Yoshii, Shunsuke Sawada, Kyoko Atsuta-Tsunoda, Kazuhiro Aoki, Shinya Tsukiji*
  Cell Chemical Biology, 29, 1446–1464 (2022) link
  bioRxiv, DOI: https://doi.org/10.1101/2021.03.16.435568
  ^†These authors contributed equally to this work.
• A photoactivatable self-localizing ligand with improved photosensitivity for chemo-optogenetic control of protein localization in living cells
  Tatsuyuki Yoshii, Choji Oki, Shinya Tsukiji*
  Bioorganic & Medicinal Chemistry Letters, 72, 128865 (2022) link
• A protocol to construct RNA-protein devices for photochemical translational regulation of synthetic mRNAs in mammalian cells
  Hideyuki Nakanishi, Tatsuyuki Yoshii, Shinya Tsukiji, Hirohide Saito*
  STAR Protocols, 3, 101451 (2022) link
• Construction of a reduction-responsive DNA microsphere using a reduction-cleavable spacer based on a nitrobenzene scaffold
  Sayuri L. Higashi, Ayaka Isogami, Junko Takahashi, Aya Shibata, Koichiro M. Hirosawa, Kenichi G.N. Suzuki, Shunsuke Sawada, Shinya Tsukiji, Kazunori Matsuura, Masato Ikeda*
  Chemistry – An Asian Journal, 17, e202200142 (2022) link
  ChemRxiv, DOI: 10.26434/chemrxiv-2022-j4gx5
• Functional visualization of NK cell-mediated killing of metastatic single tumor cells
  Hiroshi Ichise, Shoko Tsukamoto, Tsuyoshi Hirashima, Yoshinobu Konishi, Choji Oki, Shinya Tsukiji, Satoshi Iwano, Atsushi Miyawaki, Kenta Sumiyama, Kenta Terai, Michiyuki Matsuda*
  eLife, 11, e76269 (2022) link
  bioRxiv, DOI: https://doi.org/10.1101/2021.01.15.426784

2021年

• メンブレンコンタクトの化学遺伝学操作を介した膜脂質代謝の可逆制御
  吉川 優, 阿喰 萌香, 中津 史, 築地 真也
  生体機能関連化学部会ニュースレター, 36(2), 30–31 (2021) link
• A dual promoter system to monitor IFN-γ signaling in vivo at single-cell resolution
  Taisei Tanaka, Yoshinobu Konishi, Hiroshi Ichise, Shinya Tsukiji, Michiyuki Matsuda, Kenta Terai*
  Cell Structure and Function, 46, 103–111 (2021) link
• Modularly built synthetic membraneless organelles enabling targeted protein sequestration and release
  Masaru Yoshikawa, Shinya Tsukiji*
  Biochemistry, 60, 3273–3276 (2021) link
• Chemo-optogenetic protein translocation system using a photoactivatable self-localizing ligand
  Tatsuyuki Yoshii, Choji Oki, Rei Watahiki, Akinobu Nakamura, Kai Tahara, Keiko Kuwata, Toshiaki Furuta, Shinya Tsukiji*
  ACS Chemical Biology, 16, 1557–1565 (2021) link
  
  • Selected as the Supplementary Cover link
• Chemogenetic control of protein localization and mammalian cell signaling by SLIPT
  Sachio Suzuki, Yuka Hatano, Tatsuyuki Yoshii, Shinya Tsukiji*
  Methods in Molecular Biology: Mammalian Cell Engineering, 2312, 237–251 (2021) [Edited by R. Kojima, Springer Nature] link
• Second harmonic generation light quantifies the ratio of type III to total (I + III) collagen in a bundle of collagen fiber
  Shukei Sugita*, Takuya Suzumura, Akinobu Nakamura, Shinya Tsukiji, Yoshihiro Ujihara, Masanori Nakamura
  Scientific Reports, 11, 11874 (2021) link
• 細胞内相分離を理解・操作・活用する人工相分離ツール
  築地 真也, 吉川 優
  実験医学増刊「相分離 メカニズムと疾患」, 39(10), 204–210 (2021)［廣瀬哲郎, 加藤昌人, 中川真一 編, 羊土社］link
• Intravital imaging identifies the VEGF-TXA2 axis as a critical promoter of PGE2 secretion from tumor cells and immune evasion
  Yoshinobu Konishi, Hiroshi Ichise, Tetsuya Watabe, Choji Oki, Shinya Tsukiji, Yoko Hamazaki, Yasuhiro Murakawa, Akifumi Takaori-Kondo, Kenta Terai*, Michiyuki Matsuda
  Cancer Research, 81, 4124–4132 (2021) link
• 局在性リガンドによる細胞夾雑空間でのタンパク質局在操作
  築地 真也
  細胞, 53(6), 58–62 (2021) link
• Synthetic protein condensates that inducibly recruit and release protein activity in living cells
  Masaru Yoshikawa^†, Tatsuyuki Yoshii^†, Masahiro Ikuta^†, Shinya Tsukiji*
  Journal of the American Chemical Society, 143, 6434–6446 (2021) link
  bioRxiv, DOI: https://doi.org/10.1101/2020.11.09.375766
  ^†These authors contributed equally to this work.
• Light-controllable RNA-protein devices for translational regulation of synthetic mRNAs in mammalian cells
  Hideyuki Nakanishi, Tatsuyuki Yoshii, Shunsuke Kawasaki, Karin Hayashi, Keita Tsutsui, Choji Oki, Shinya Tsukiji, Hirohide Saito*
  Cell Chemical Biology, 28, 662–674 (2021) link
  
  • Selected as the Front Cover link

2020年

• 光応答性局在分子システムによる細胞操作
  吉井 達之, 築地 真也
  生物工学, 98(12), 659–663 (2020) link
• 低分子リガンドに特異的に結合する人工抗体の創製
  都築 成晃, 吉井 達之, 近藤 太志, 藤野 公茂, 林 剛介, 築地 真也, 村上 裕
  生体機能関連化学部会ニュースレター, 35(2), 24–25 (2020) link
• Protein-recruiting synthetic molecules targeting the Golgi surface
  Shunsuke Sawada, Akinobu Nakamura, Tatsuyuki Yoshii, Keiko Kuwata, Fubito Nakatsu, Shinya Tsukiji*
  Chemical Communications, 56, 15422–15425 (2020) link
  
  • Selected as a ChemComm HOT Article
• 生細胞内に人工ドロプレットをつくる：合成相分離生物学
  築地 真也
  現代化学増刊「相分離生物学の全貌」, 第V部 44章, 220–224 (2020)［白木賢太郎 編, 東京化学同人］link
• 単一細胞内の局所プロトン濃度を測る蛍光センサー：古典的手法から新展開まで
  築地 真也
  電気化学, 88(3), 240–245 (2020) link
• An improved intracellular synthetic lipidation-induced plasma membrane anchoring system for SNAP-tag fusion proteins
  Tatsuyuki Yoshii^†, Kai Tahara^†, Sachio Suzuki, Yuka Hatano, Keiko Kuwata, Shinya Tsukiji*
  Biochemistry, 59, 3044–3050 (2020) link
  bioRxiv, DOI: https://doi.org/10.1101/2020.04.09.035188
  ^†These authors contributed equally to this work.
• Golgi recruitment assay for visualizing small-molecule ligand–target engagement in cells
  Sachio Suzuki, Masahiro Ikuta, Tatsuyuki Yoshii, Akinobu Nakamura, Keiko Kuwata, Shinya Tsukiji*
  Chemical Communications, 56, 7961–7964 (2020) link
  ChemRxiv, DOI: 10.26434/chemrxiv.12219890
• 生命現象の操作と可視化のための細胞内人工相分離ツール
  吉川 優, 吉井 達之, 築地 真也
  生物工学, 98(5), 246–250 (2020) link
• Hoechst-tagged fluorescein diacetate for the fluorescence imaging-based assessment of stomatal dynamics in Arabidopsis thaliana
  Yousuke Takaoka, Saki Miyagawa, Akinobu Nakamura, Syusuke Egoshi, Shinya Tsukiji*, Minoru Ueda*
  Scientific Reports, 10, 5333 (2020) link
• Designer palmitoylation motif-based self-localizing ligand for sustained control of protein localization in living cells and Caenorhabditis elegans
  Akinobu Nakamura, Choji Oki, Shunsuke Sawada, Tatsuyuki Yoshii, Keiko Kuwata, Andrew K. Rudd, Neal K. Devaraj, Kentaro Noma, Shinya Tsukiji*
  ACS Chemical Biology, 15, 837–843 (2020) link
• Engineering orthogonal, plasma membrane-specific SLIPT systems for multiplexed chemical control of signaling pathways in living single cells
  Akinobu Nakamura, Choji Oki, Kenya Kato, Satoko Fujinuma, Gembu Maryu, Keiko Kuwata, Tatsuyuki Yoshii, Michiyuki Matsuda, Kazuhiro Aoki, Shinya Tsukiji*
  ACS Chemical Biology, 15, 1004–1015 (2020) link
  ChemRxiv, DOI: 10.26434/chemrxiv.8222456
• Development of cell-penetration PG-surfactants and its application in external peptide delivery to cytosol
  Natsumi Sumito, Shuhei Koeda, Naoki Umezawa, Yasumichi Inoue, Shinya Tsukiji, Tsunehiko Higuchi, Toshihisa Mizuno*
  Bioconjugate Chemistry, 31, 821–833 (2020) link
• Chemogenetic control of protein anchoring to endomembranes in living cells with lipid-tethered small molecules
  Akinobu Nakamura, Rika Katahira, Shunsuke Sawada, Eri Shinoda, Keiko Kuwata, Tatsuyuki Yoshii, Shinya Tsukiji*
  Biochemistry, 59, 205–211 (2020) link
  ChemRxiv, DOI: 10.26434/chemrxiv.9762566

2019年

• photoSLIPTによる細胞内分子の光操作と多色イメージング
  沖 超二, 吉井 達之, 築地 真也
  生体機能関連化学部会ニュースレター, 34(2), 32–33 (2019) link
• 分子夾雑化学から切り拓くオルガネラ局在分子テクノロジー
  築地 真也
  CMCB News Letter, No.4, 4 (2019)（新学術領域「分子夾雑化学」ニュースレター）
• 細胞夾雑空間と局在分子化学
  吉井 達之, 築地 真也
  現代化学, 581, 60–65 (2019) link
• Synthesis of transmembrane molecules by click chemistry
  Wataru Hatanaka, Hiroki Takeuchi, Minaho Koga, Taka-aki Ryujin, Akihiro Kishimura, Yoshiki Katayama, Shinya Tsukiji, Takeshi Mori
  Chemistry Letters, 48, 433–436 (2019) link

2018年

• 化合物で細胞内分子の局在を操る〜SLIPTテクノロジーの可能性〜
  築地 真也
  生命化学研究レター, No.56, 7–12 (2018) link

2017年

• Ratiometric fluorescence imaging of nuclear pH in living cells using Hoechst-tagged fluorescein
  Akinobu Nakamura, Shinya Tsukiji
  Bioorganic & Medicinal Chemistry Letters, 27, 3127–3130 (2017) link
• Noncanonical function of a small-molecular virulence factor coronatine against plant immunity: an in vivo raman imaging approach
  Minoru Ueda, Syusuke Egoshi, Kosuke Dodo, Yasuhiro Ishimaru, Hiroyuki Yamakoshi, Takeshi Nakano, Yousuke Takaoka, Shinya Tsukiji, Mikiko Sodeoka
  ACS Central Science, 3, 462–472 (2017) link

2016年

• 独自の分子デザインによる次世代生命制御を目指して
  築地 真也
  Peptide Newsletter Japan, No.102, 2–5 (2016) link
• A set of organelle-localizable reactive molecules for mitochondrial chemical proteomics in living cells and brain tissues
  Yuki Yasueda, Tomonori Tamura, Alma Fujisawa, Keiko Kuwata, Shinya Tsukiji, Shigeki Kiyonaka, Itaru Hamachi
  Journal of the American Chemical Society, 138, 7592–7602 (2016) link
• Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity
  Yohei Shiina, Tomohiro Muto, Zhili Zhang, Ahmad Baihaqie, Takamasa Yoshizawa, Hye-in J. Lee, Eulsoon Park, Shinya Tsukiji, Koichi Takimoto
  Scientific Reports, 6, 26290 (2016) link
• タンパク質の細胞内局在を操る小分子リガンド
  築地 真也
  YAKUGAKU ZASSHI, 136(1), 9–16 (2016) link

2015年

• タンパク質の細胞内局在を操る化合物ー局在性リガンド
  築地 真也
  生体の科学, 66(2), 95–101 (2015) link
• Ligand-directed tosyl chemistry for selective native protein labeling in vitro, in cells, and in vivo
  Shinya Tsukiji, Itaru Hamachi
  Methods in Molecular Biology: Site-Specific Protein Labeling, 1266, 243–263 (2015) [Edited by A. Gautier and M. J. Hinner, Springer] link

2014年

• Ligand-directed tosyl chemistry for in situ native protein labeling and engineering in living systems: from basic properties to applications
  Shinya Tsukiji, Itaru Hamachi
  Current Opinion in Chemical Biology, 21, 136–143 (2014) link
• Hoechst tagging: a modular strategy to design synthetic fluorescent probes for live-cell nucleus imaging
  Akinobu Nakamura, Kazumasa Takigawa, Yasutaka Kurishita, Keiko Kuwata, Manabu Ishida, Yasushi Shimoda, Itaru Hamachi, Shinya Tsukiji
  Chemical Communications, 50, 6149–6152 (2014) link

2013年

• タンパク質の細胞内局在を変える化合物ー合成化合物で細胞を操るための新しい方法論ー
  築地 真也
  化学と工業, 66(10), 827–828 (2013) link
• Synthetic self-localizing ligands that control the spatial location of proteins in living cells
  Manabu Ishida, Hideaki Watanabe, Kazumasa Takigawa, Yasutaka Kurishita, Choji Oki, Akinobu Nakamura, Itaru Hamachi, Shinya Tsukiji
  Journal of the American Chemical Society, 135, 12684–12689 (2013) link
  
  • Featured in Chemical & Engineering News [S. Borman, “Moving vans for cellular proteins” Chem. Eng. News, 91(34), 5 (2013)] link
  • Featured in F1000Prime by R. Weatherman and D. Triggle.
  • Featured in JACS Spotlights [J. M. Perkel, “Location, location, location” J. Am. Chem. Soc., 135, 13221 (2013)] link
  • Featured in ACS Chemical Biology Spotlight [S. A. Webb, “Controlling protein movement within cells” ACS Chem. Biol., 8, 2109–2111 (2013)] link
  • Featured in 現代化学 2014年 5月号［井上尊生 “有機合成化学と細胞生物学のケミカルダイメライゼーションー細胞機能の全合成に向けてー”］link
• Fluorophore labeling of native FKBP12 by ligand-directed tosyl chemistry allows detection of its molecular interactions in vitro and in living cells
  Tomonori Tamura, Yoshiyuki Kioi, Takayuki Miki, Shinya Tsukiji, Itaru Hamachi
  Journal of the American Chemical Society, 135, 6782–6785 (2013) link
• 細胞の中の狙った天然タンパク質を合成小分子で修飾する
  築地 真也
  化学と教育, 61(2), 62–63 (2013) link
• 局在性リガンドによる細胞内情報伝達誘導システム
  築地 真也, 浜地 格
  未来材料, 13(2), 11–16 (2013) link

2012年

• 局在性リガンド：細胞機能制御のための新しい分子コンセプト
  築地 真也
  生体機能関連化学部会ニュースレター, 27(3), 9–12 (2012) link
• Native FKBP12 engineering by ligand-directed tosyl chemistry: labeling properties and application to photo-cross-linking of protein complexes in vitro and in living cells
  Tomonori Tamura, Shinya Tsukiji, Itaru Hamachi
  Journal of the American Chemical Society, 134, 2216–2226 (2012) link

2011年

• 細胞内在性タンパク質の選択的化学修飾とエンジニアリング
  築地 真也, 石田 学, 浜地 格
  生化学, 83(8), 746–751 (2011) link
• Chemical cell-surface receptor engineering using affinity-guided, multivalent organocatalysts
  Hangxiang Wang, Yoichiro Koshi, Daishiro Minato, Hiroshi Nonaka, Shigeki Kiyonaka, Yasuo Mori, Shinya Tsukiji, Itaru Hamachi
  Journal of the American Chemical Society, 133, 12220–12228 (2011) link
• Stiff, multistimuli-responsive supramolecular hydrogels as unique molds for 2D/3D microarchitectures of live cells
  Harunobu Komatsu, Shinya Tsukiji, Masato Ikeda, Itaru Hamachi
  Chemistry – An Asian Journal, 6, 2368–2375 (2011) link
• Construction of a ¹⁹F-lectin biosensor for glycoprotein imaging by using affinity-guided DMAP chemistry
  Yedi Sun, Yousuke Takaoka, Shinya Tsukiji, Michiko Narazaki, Tetsuya Matsuda, Itaru Hamachi
  Bioorganic & Medicinal Chemistry Letters, 21, 4393–4396 (2011) link
• Mechanisms of chemical protein ¹⁹F-labeling and NMR-based biosensor construction in vitro and in cells using self-assembling ligand-directed tosylate compounds
  Yousuke Takaoka, Yedi Sun, Shinya Tsukiji, Itaru Hamachi
  Chemical Science, 2, 511–520 (2011) link

2010年

• 生体内在性タンパク質の"tracelessな"アフィニティラベリングツール
  築地 真也, 浜地 格
  化学フロンティア「生命現象を理解する分子ツールーイメージングから生体機能解析までー」, III部 16章, 127–134 (2010)［浜地格・二木史朗 編, 化学同人］link
• アフィニティラベル化
  築地 真也, 浜地 格
  酵素利用技術大系ー基礎・解析から改変・高機能化・産業利用までー, 第4編 第2章 第1節 2, 274–278 (2010)［小宮山真 監修, エヌ・ティー・エス］link
• Disassembly-driven turn-on fluorescent nanoprobes for selective protein detection
  Keigo Mizusawa, Yoshiyuki Ishida, Yousuke Takaoka, Masayoshi Miyagawa, Shinya Tsukiji, Itaru Hamachi
  Journal of the American Chemical Society, 132, 7291–7293 (2010) link

2009年

• Rapid and efficient induction of an endogenous cell signaling event by subcellular targeting of a synthetic ligand
  Shuhei Hashiro, Shinya Tsukiji, Teruyuki Nagamune
  Journal of the American Chemical Society, 131, 13568–13569 (2009) link
  
  • Featured in Nature Methods "News In Brief" [Nat. Methods, 6, 791 (2009)] link
• Self-assembling nanoprobes that display off/on ¹⁹F nuclear magnetic resonance signals for protein detection and imaging
  Yousuke Takaoka, Takashi Sakamoto, Shinya Tsukiji, Michiko Narazaki, Tetsuya Matsuda, Hidehito Tochio, Masahiro Shirakawa, Itaru Hamachi
  Nature Chemistry, 1, 557–561 (2009) link
  
  • Featured in News & Views of Nature Chemistry [M. A. Azagarsamy, S. Thayumanavan, “Making sense of disassembly” Nat. Chem., 1, 523–524 (2009)] link
• Site-specific covalent labeling of His-tag fused proteins with a reactive Ni(II)-NTA probe
  Sho-hei Uchinomiya, Hiroshi Nonaka, Sho-hei Fujishima, Shinya Tsukiji, Akio Ojida, Itaru Hamachi
  Chemical Communications, 5880–5882 (2009) link
• 分子イメージングの新ステージー細胞有機化学による斬新な化学プローブ分子の誕生ー
  高岡 洋輔, 築地 真也, 浜地 格
  化学, 64(7), 29–34 (2009)
• Quenched ligand-directed tosylate reagents for one-step construction of turn-on fluorescent biosensors
  Shinya Tsukiji, Hangxiang Wang, Masayoshi Miyagawa, Tomonori Tamura, Yousuke Takaoka, Itaru Hamachi
  Journal of the American Chemical Society, 131, 9046–9054 (2009) link
• Ligand-directed tosyl chemistry for protein labeling in vivo
  Shinya Tsukiji, Masayoshi Miyagawa, Yousuke Takaoka, Tomonori Tamura, Itaru Hamachi
  Nature Chemical Biology, 5, 341–343 (2009) link
  
  • Featured in News & Views of Nature Chemical Biology [Q. Lin, R. K. V. Lim, “Traceless native protein labeling in mice” Nat. Chem. Biol., 5, 275–276 (2009)] link
  • Featured in F1000Prime by K. Johnsson, R. Weatherman, and A. Barrios.
• Sortase-mediated ligation: a gift from Gram-positive bacteria to protein engineering
  Shinya Tsukiji, Teruyuki Nagamune
  ChemBioChem, 10, 787–798 (2009) link

2008年

• A bromocoumarin-based linker for synthesis of photocleavable peptidoconjugates with high photosensitivity
  Kentaro Katayama, Shinya Tsukiji, Toshiaki Furuta, Teruyuki Nagamune
  Chemical Communications, 5399–5401 (2008) link
• Affinity-labeling-based introduction of a reactive handle for natural protein modification
  Haruto Wakabayashi, Masayoshi Miyagawa, Yoichiro Koshi, Yousuke Takaoka, Shinya Tsukiji, Itaru Hamachi
  Chemistry – An Asian Journal, 3, 1134–1139 (2008) link
• A caged phosphopeptide-based approach for photochemical activation of kinases in living cells
  Takashi Kawakami, Huan Cheng, Shuhei Hashiro, Yasushi Nomura, Shinya Tsukiji, Toshiaki Furuta, Teruyuki Nagamune
  ChemBioChem, 9, 1583–1586 (2008) link
• Covalent split protein fragment-DNA hybrids generated through N-terminus-specific modification of proteins by oligonucleotides
  Shuji Takeda, Shinya Tsukiji, Hiroshi Ueda, Teruyuki Nagamune
  Organic & Biomolecular Chemistry, 6, 2187–2194 (2008) link
• Site-specific protein modification on living cells catalyzed by sortase
  Tsutomu Tanaka, Teruyasu Yamamoto, Shinya Tsukiji, Teruyuki Nagamune
  ChemBioChem, 9, 802–807 (2008) link
  
  • Selected as the Front Cover link
• Successful control of aggregation and folding rates during refolding of denatured lysozyme by adding N-methylimidazolium cations with various N'-substituents
  Satoshi Yamaguchi, Etsushi Yamamoto, Shinya Tsukiji, Teruyuki Nagamune
  Biotechnology Progress, 24, 402–408 (2008) link
• Target-specific chemical acylation of lectins by ligand-tethered DMAP catalysts
  Yoichiro Koshi, Eiji Nakata, Masayoshi Miyagawa, Shinya Tsukiji, Tomohisa Ogawa, Itaru Hamachi
  Journal of the American Chemical Society, 130, 245–251 (2008) link

2007年

• Non-enzymatic covalent protein labeling using a reactive tag
  Hiroshi Nonaka, Shinya Tsukiji, Akio Ojida, Itaru Hamachi
  Journal of the American Chemical Society, 129, 15777–15779 (2007) link
• Construction of a small-molecule-integrated semisynthetic split intein for in vivo protein ligation
  Tomomi Ando, Shinya Tsukiji, Tsutomu Tanaka, Teruyuki Nagamune
  Chemical Communications, 4995–4997 (2007) link
  
  • Selected as a Hot Paper
  • Featured in Chemical Biology (The Royal Society of Chemistry) [K. Too, “Cells surface in semisynthesis” Chem. Biol., 2, B91 (2007)] link
• 細胞を指向した化学による蛋白質の蛍光ラベル化ー合成蛍光色素を用いた細胞内蛋白質ラベリングと半合成バイオセンサーの創製ー
  築地 真也, 浜地 格
  蛋白質核酸酵素 2007年10月号増刊「ケミカルバイオロジー」, 52(13), 1581–1587 (2007)［長野哲雄・長田裕之・菊地和也・上杉志成 編集, 共立出版］link
• Development of new methods to introduce unnatural functional molecules into native proteins for protein engineering
  Eiji Nakata, Shinya Tsukiji, Itaru Hamachi
  Bulletin of the Chemical Society of Japan, 80, 1268–1279 (2007) link

2006年

• 細胞内情報伝達をあやつる
  築地 真也, 菅 裕明, 長棟 輝行
  バイオニクス, 3月号, 46–51 (2006)

2005年

• A cysteine-appended deoxyuridine for the postsynthetic DNA modification using native chemical ligation
  Shuji Takeda, Shinya Tsukiji, Teruyuki Nagamune
  Tetrahedron Letters, 46, 2235–2238 (2005) link

2004年

• Solid-phase artificial chaperone-assisted refolding using insoluble β-cyclodextrin-acrylamide copolymer beads
  Satoshi Yamaguchi, Chai Hong, Teruhisa Mannen, Shinya Tsukiji, Teruyuki Nagamune
  Biotechnology Letters, 26, 1787–1791 (2004) link
• Ribozymes that use redox cofactors
  Shinya Tsukiji, Krishna Ramaswamy, Hiroaki Suga
  Pure and Applied Chemistry, 76, 1525–1536 (2004) link
• Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation
  Shuji Takeda, Shinya Tsukiji, Teruyuki Nagamune
  Bioorganic & Medicinal Chemistry Letters, 14, 2407–2410 (2004) link
• Reduction of an aldehyde by a NADH/Zn²⁺-dependent redox active ribozyme
  Shinya Tsukiji, Swetansu B. Pattnaik, Hiroaki Suga
  Journal of the American Chemical Society, 126, 5044–5045 (2004) link

2003年

• An alcohol dehydrogenase ribozyme
  Shinya Tsukiji, Swetansu B. Pattnaik, Hiroaki Suga
  Nature Structural Biology, 10, 713–717 (2003) link

2002年

• 修飾ミオグロビンによる水の光分解をめざして
  築地 真也, 浜地 格
  バイオサイエンスとインダストリー, 60(4), 245–246 (2002)
• Semisynthetic hemoproteins using cofactor engineering: toward supramolecular protein-based photosynthetic system
  Shinya Tsukiji, Itaru Hamachi
  Supramolecular Chemistry, 14, 133–142 (2002) link

2001年

• Zn(II) dipicolylamine-based artificial receptor as a new entry for surface recognition of α-helical peptides in aqueous solution
  Yasuko Mito-oka, Shinya Tsukiji, Takashi Hiraoka, Noriyuki Kasagi, Seiji Shinkai, Itaru Hamachi
  Tetrahedron Letters, 42, 7059–7062 (2001) link

2000年

• Direct comparison of electron transfer properties of two distinct semisynthetic triads with non-protein based triad: unambiguous experimental evidences on protein matrix effects
  Yi-Zhen Hu, Hiroshi Takashima, Shinya Tsukiji, Seiji Shinkai, Teruyuki Nagamune, Shigero Oishi, Itaru Hamachi
  Chemistry – A European Journal, 6, 1907–1916 (2000) link
  
  • Selected as the Front Cover link
• Coupling covalent and noncovalent electron transfer in a catenane-type donor-sensitizer-acceptor triad
  Yi-Zhen Hu, Shinya Tsukiji, Seiji Shinkai, Shigero Oishi, Heinz Dürr, Itaru Hamachi
  Chemistry Letters, 29, 442–443 (2000) link
• Construction of artificial photosynthetic reaction centers on a protein surface: vectorial, multistep, and proton-coupled electron transfer for long-lived charge separation
  Yi-Zhen Hu, Shinya Tsukiji, Seiji Shinkai, Shigero Oishi, Itaru Hamachi
  Journal of the American Chemical Society, 122, 241–253 (2000) link

1999年

• カリックスアレーンを基体とした抗体ミミック分子による蛋白質表面の認識
  築地 真也
  化学と工業, 52(10), 1301 (1999)
• Electron transfer from Zn-protoporphyrin IX to ruthenium ammine attached at His63 of reconstituted cytochrome b₅₆₂
  Itaru Hamachi, Hiroshi Takashima, Shinya Tsukiji, Seiji Shinkai, Teruyuki Nagamune, Shigero Oishi
  Chemistry Letters, 28, 551–552 (1999) link
• 光機能性蛋白質の創成を目指してー蛋白質マトリックス中での光電子移動反応ー
  築地 真也
  生命化学研究レター, No.1, 3 (1999) link
• A convenient synthesis of a Ru(bpy)₃-based catenane-type triad and its incorporation into a protein scaffold
  Yi-Zhen Hu, Shinya Tsukiji, Seiji Shinkai, Itaru Hamachi
  Chemistry Letters, 28, 517–518 (1999) link
• Direct observation of the ferric-porphyrin cation radical as an intermediate in the phototriggered oxidation of ferric- to ferryl-heme tethered to Ru(bpy)₃ in reconstituted myoglobin
  Itaru Hamachi, Shinya Tsukiji, Seiji Shinkai, Shigero Oishi
  Journal of the American Chemical Society, 121, 5500–5506 (1999) link

1998年

• Design and semisynthesis of photoactive myoglobin bearing ruthenium tris(2,2'-bipyridine) using cofactor-reconstitution
  Itaru Hamachi, Shigeaki Tanaka, Shinya Tsukiji, Seiji Shinkai, Shigero Oishi
  Inorganic Chemistry, 37, 4380–4388 (1998) link

1997年

• Photocontrol of the redox state of ruthenium-tris(bipyridine)-appended cytochrome b₅₆₂
  Itaru Hamachi, Shigeaki Tanaka, Shinya Tsukiji, Seiji Shinkai, Masafumi Shimizu, Teruyuki Nagamune
  Chemical Communications, 1735–1736 (1997) link

1996年

• Efficient photogeneration of oxidizing (compound II-like) species of semisynthetic myoglobin appending ruthenium tris(2,2'-bipyridine)
  Itaru Hamachi, Shinya Tsukiji, Shigeaki Tanaka, Seiji Shinkai
  Chemistry Letters, 25, 751–752 (1996) link